Curriculum Vitae -
Yaron S. Rabinowitz, M.D.
August 2007
BUSINESS ADDRESS:
Cornea-Genetic Eye Institute
50 North La Cienega Blvd, #340
Beverly Hills, CA 90211
Telephone:
310.423.9640
Fax Number:
310.423.9649
CLINICAL TITLE:
Director of Research, Division of Ophthalmology
Cedars-Sinai Medical Center
Los Angeles, California
ACADEMIC APPOINTMENTS:
Director of Research
Division of Ophthalmology
Cedars-Sinai Medical Center
Clinical Professor
Department of Ophthalmology
Jules Stein Eye Institute
U.C.L.A. School of Medicine
CLINICAL INVESTIGATOR:
Keratoconus Genetics Research Program
National Institutes of Health
Mentor: NIH funded KO8 Grant
Mapping Ocular Genes in Down Syndrome
Custom Cornea Clinical Trials,
FDA study, Alcon/Autonomous LADARvision system
Hyperopic Astigmatism Study,
FDA study, Visx INC
Myopia and Hyperopia LASIK Study
FDA study, Autonomous Technologies Inc.
ACADEMIC HONORS AND AWARDS:
2007:
Appointed to Cornea Compass Panel, Educational arm of the American Academy of Ophthalmology
Chair for Ectasia Symposium, Pan American Association of Ophthalmology
Organizing Committee for Cornea Subspecialty Day, American Academy of Ophthalmology
Joint Chair for ISRS Symposium, American Academy of Ophthalmology
2006:
International Society of Refractive Surgery and American Academy of Ophthalmology, Michael Kritzinger Award for Excellence and Contributions to the Field of Refractive Surgery
2005:
Honored Guest French Eye Society, Paris, France; Keynote Lecture -Current Concepts in Keratoconus
2004:
Best Paper Award. American Society of Cataract and Refractive Surgery, San Diego, May 2004
2003:
Elected to the Board of The Cornea Society (Academic Society representing cornea specialists worldwide; Dr. Rabinowitz is one of only twelve cornea specialists in the world)
2001:
U.C.L.A. Alumni Association Research Award
2000:
American Academy of Ophthalmology Honor Award
1999:
VISX Star Award; Dr. Rabinowitz is in the top five percent of the refractive surgeons in the USA
Invited panelist, NEI Panel for Postdoctoral Research Students
1997:
Invited panelist. Panel for Human Genomics Planning Committee. National Eye Institutes of Health
1997:
Invited panelist. NIH Corneal Diseases Panel; five-year program planning Committee. National Eye Institutes of Health
1994:
U.C.L.A. Alumni Association Research Award
1993:
Fisons, Research in Immunology and Contact Lens Award
1990:
Contact Lens Association of Ophthalmologists, Research in Immunology and Contact Lens Award
1987:
Mencion de Honor’, Resident Essay Competition, Pan American Association of Ophthalmology
Shumaker Award for Resident Research in Ophthalmology, Pennsylvania Academy of Ophthalmology
1979:
Invitational essay to commemorate 150th Anniversary of the University of Cape Town (U.C.T.), Cape Town, South Africa
1978:
James T. Louw Prize, Medical student essay, University of Cape Town, South Africa
1973:
Senator F.S. Malan Scholarship Academic achievement U.C.T
1972:
Bertha and Ellis Silverman Scholarship, University of Cape Town
1971:
Head Student, Herzlia High School, Cape Town and Alfred Honikman Prize for Leadership
EDUCATION:
Ocular and Molecular
Genetics Fellowship:
1989–1990
Wilmer Eye Institute and the Department of Medicine
The Johns Hopkins University
Baltimore, Maryland
Corneal/External Disease Fellowship:
1988–1989
Estelle Doheny Eye Clinic
University of Southern California
Los Angeles, California
Ophthalmology Residency:
1985–1988
Pennsylvania State University
Hershey, Pennsylvania
Family Medicine Training:
1981–1984
Surgery, OB/GYN, Pediatrics,
Groote Schuur Hospital and Red Cross Children's Hospital
and Private Practice of Medicine
Cape Town, South Africa
Internship:
1979–1980
Internal Medicine/Surgery
Groote Schuur Hospital
Cape Town, South Africa
University and Medical School:
1973–1979
University of Cape Town
Groote Schuur Hospital
Cape Town, South Africa
High School:
1971
Herzlia High School
Cape Town, South Africa
Research Grants:
2007–2012
National Eye Institutes of Health: R01
“Genes for Keratoconus;”
($3,800,000);
2006–2008
Eye Birth Defects Research Foundation Grant
“Early Detection and Genetics of Keratoconus”
($250,000 annually)
2005–2008
Skirball Foundation Grant
“Identifying Genes in Keratoconus”
($60,000 annually)
2001–2007
National Eye Institutes of Health: R01
“Genes for Keratoconus”
($2,800,000)
2000–2005
Mentor: K08 NIH Grant
“Mapping Ocular Genes in Down Syndrome”
($600,000)
1999
March of Dimes
Support for “Genetic Disease and the Eye Conference”
($5,000)
1996–2000
National Eye Institutes of Health: R01 Award
“Genetic Factors in Keratoconus”
($1,700,000)
1993–1996
National Eye Institutes of Health R01 Award
“Genetic Factors in Keratoconus”
($700,000)
1993
Cedars-Sinai Biomedical Research Institute
“Young Investigator's Award”
($10,000)
1991
Schoellerman Trust Fund
Research in Ophthalmology Award
($10,000)
1989
Fight for Sight, Research to Prevent Blindness
Research Fellowship Award
($20,000)
1989
Knights Templar Eye Foundation Research Award
($20,000)
1989
National Keratoconus Foundation Research Award
($10,000)
Published Scientific Manuscripts:
1. Rabinowitz YS, Ladda RL, Sassani JW, Eyster ME: Co-segregation of X-linked retinitis pigmentosa and hemophilia; A. American Journal of Ophthalmology; 105:46-56 (1988).
2. Rabinowitz YS, Ladda RL, Sassani JW, Eyster ME: An approach to a genetic eye disorder; Trans Penn Acad Ophthalmology; 27:453-457 (1988).
3. Johnson LN, Rabinowitz YS, Hepler RS: Retinitis pigmentosa presenting as hemianopsia respecting the vertical meridian; Archives of Neurology; 28:43-45 (1989).
4. Rabinowitz YS, McDonnell PJ: Computerized corneal topography in keratoconus; Refractive and Corneal Surgery; Vol 5, 6:40-408 (1989).
5. Smith SG, Rabinowitz YS, Sassani JW, Smith RE: Keratoconus granular and lattice dystrophies in the same eye; American Journal of Ophthalmology; 108:608-9 (1989).
6. Rabinowitz YS, McDonnell PJ: Corneal topography of early keratoconus; American Journal of Ophthalmology; 108:746-747 (1989).
7. Rabinowitz YS, Garbus JJ, McDonnell PJ: Computer-assisted corneal topography in family members of patients with keratoconus; Archives of Ophthalmology; 108:365-371 (1990).
8. Rabinowitz YS, Garbus JJ, Garbus C, McDonnell PJ: Contact lens selection for keratoconus using a computer-assisted videophotokeratoscope; CLAO J; 17:88-93 (1991).
9. Rabinowitz YS, Klyce SD, Krachmer JH et al: Videokeratography, keratoconus, and refractive surgery; Opinion; Refractive and Corneal Surgery; 5:403-7 (1992).
10. Rabinowitz YS, Maumenee IH, Lundergan MK, Puffenberg E, et al: Molecular genetics in autosomal dominant keratoconus; Cornea; 11(4):302-308 (1992).
11. Sassani JW, Rabinowitz YS, Smith SG: Keratoconus and bilateral lattice-granular corneal dystrophies; Cornea; 11(4):343-350 (1992).
12. Rabinowitz YS, Nesburn AB, McDonnell PJ: Videokeratography of the fellow eye in unilateral keratoconus; Ophthalmology; 100:181-6 (1993).
13. Rabinowitz YS: Reply to Hustead JD: Detection of keratoconus before keratorefractive surgery; Ophthalmology; 100:975 (1993).
14. Rabinowitz YS: Corneal Topography (Review Article). Current Opinions in Ophthalmology; Current Science; 4; IV: 69-74 (1993).
15. Waring GO, Rabinowitz YS, Sugar J, et al: Nomenclature for Keratoconus Suspects; Opinions; Refractive and Corneal Surgery; 9; 3:219-222 (1993).
16. Rabinowitz YS: Reply to Wolgang-Behrens; Detection of keratoconus before refractive surgery; Ophthalmology; 101:5:794-5 (1994).
17. Rabinowitz YS: Corneal topography: diagnosis and management of corneal disease; Optometry Today; 6:14-16 (1994).
18. Rabinowitz YS: Corneal topography: co-management: management of corneal astigmatism; Optometry Today; 7:20-21 (1994).
19. Nesburn AB, Bahri S, Salz J, Rabinowitz YS, et al: Keratoconus in photorefractive keratectomy candidates detected by computer-assisted Videokeratography; Refractive and Corneal Surgery; 11:3:194-201 (1995).
20. Rabinowitz YS: Corneal Topography 1994; Current Opinions in Ophthalmology; Current Science; 6:4:57-62 (1995).
21. Rabinowitz YS: Videokeratography indices to aid in screening for keratoconus; Refractive and Corneal Surgery; 11:371-379 (1995).
22. Parker J, Ko W, Pavlopoulos G, Wolfe P, Rabinowitz YS, Feldman S: Videokeratography of keratoconus in monozygotic twins; Journal of Refractive Surgery; 12:180-183 (1996).
23. Rabinowitz YS, Yang H, Elashoff J, Akkina J, Rotter J: Videokeratography database of normal human corneas. British Journal of Ophthalmology; 80:610-616 (1996).
24. Rabinowitz YS: Tangential vs saggital videokeratographs in the “early” detection of keratoconus; American Journal of Ophthalmology; 122:6:888-889 (1996).
25. Bron A, Rabinowitz YS: Corneal dystrophies and keratoconus; Current Opinion in Ophthalmology; 7 IV: 71-82 (1996).
26. Sczhotka L, Rabinowitz YS, Yang H: The influence of contact lens wear on the topography of keratoconus; CLAO J; 22:4:270-273 (1996).
27. Rabinowitz YS: Review of Corneal Topography: The Clinical Atlas. Lucio Burrato, Ed.; American Journal of Ophthalmology; 123:3:431-432 (1997).
28. Dibbern K, Rabinowitz YS, Shorr N, Graham J: Surgical correction of incomplete Fraser’s syndrome; American Journal of Ophthalmology; 124:1:107-109 (1997).
29. Rabinowitz YS: Keratoconus: update and new advances (Major review); Survey of Ophthalmology; 42:4:297- 319, (1998).
30. Rabinowitz YS, Rasheed K, Yang H, Elashoff J, Rotter J. Accuracy of ultrasonic pachymetry and Videokeratography in detecting keratoconus; Journal of Cataract and Refractive Surgery; 24: 196-201, (1998).
31. Rabinowitz YS: Keratoconus and corneal dystrophies In: VISION RESEARCH: A National Plan, 1999-2003; Report of Corneal Diseases Panel; pgs. 43-44, 54, (1998).
32. Zaidman G, Rabinowitz YS, Forstot L: Optical iridectomy for corneal opacities in Peter’s Anomaly; Journal of Cataract and Refractive Surgery; 24:719-72 (1998).
33. Rasheed K, Rabinowitz YS, Remba M, Remba D: Inter- and Intra-observer reliability of a classification scheme for corneal topographic patterns; British Journal of Ophthalmology; 82:1401-06 (1998).
34. Rasheed K, Rabinowitz YS: Superficial lamellar keratectomy using the Hansatome for the treatment of severe corneal haze following photorefractive keratectomy; Journal of Cataract and Refractive Surgery; 25:1184-1186 (1999).
35. Rasheed K, Rabinowitz YS: Flourescein test to detect stria following laser-in-situ keratomeliusis; American Journal of Ophthalmology; 6:717-8 (1999).
36. Faktorovich E, Rabinowitz YS: A new technique for penetrating keratoplasty in patients with low scleral rigidity; JCRS; 25:882-884 (1999).
37. Rabinowitz YS, Rasheed K: KI-SA% system a new videokeratography system for the early detection of keratoconus; Journal of Cataract and Refractive Surgery; 25:10: 1327-1336 (1999).
38. Kim WJ, Rabinowitz YS, Meisler DM, Wilson SE: Keratocyte Apoptosis associated with keratoconus; Experimental Eye Research; 69:5:475-81, (Nov. 1999).
39. Wang Y, Rabinowitz YS, Rotter J, Yang H: Genetic epidemiological study of keratoconus: evidence for a major gene determination; American Journal of Medical Genetics; 93:403-409 (2000).
40. Bergwerk K, Rabinowitz YS, Glasgow B: Cornea transplant in a patient with mucopolysaccharidosis type VII; Ophthalmic Genetics; Vol 21:1:17-20 (2000).
41. Rasheed K, Rabinowitz YS: Surgical treatment of advanced pellucid marginal degeneration; Ophthalmology; 21:1:17-20 (2000).
42. McDonald M, Carr J, Frantz J, Kozarsky A, Maguen E, Nesburn A, Rabinowitz YS, et al.: GO. Laser-in-situ keratomilieusis for myopia up to –11 diopters with up to –5 diopters of astigmatism with the summit autonomous LADARVision Excimer Laser System; Ophthalmology; 108:2: 309-316 (2001).
43. Salz JJ, Stevens CA, McDonald M, Carr J, et al.: GO. LASIK correction of spherical hyperopia, hyperopic astigmatism, and mixed astigmatism with the LADARVision excimer laser system; Ophthalmology; 109(9):1647-56 (Sept. 2002).
44. Rabinowitz YS: Pellucid marginal degeneration. An unsuspecting trap for the refractive surgeon; Refractive Eye Care; (October 2002).
45. Bergwerk KL, Rabinowitz YS, Falk RL: Quality of life related to visual function in three young adults with mucopolysaccharidoses; Scientific World Journal; 3:922-9 (Oct. 5 2003).
46. Rabinowitz YS: Genetics of keratoconus (review). Ophthalmol Clin North Am; 16(4)607-20 (Dec. 16, 2003).
47. Bergwerk KL, Schorr N, Rabinowitz YS: Visual function in an 11-year-old with Fraser’s cryptophthalmos syndrome; Am J Ophthalmol; 137(3)591-3 (Mar. 2004).
48. Li X, Rabinowitz YS, Rasheed K, Yang H: Longitudinal study of the normal eyes in unilateral keratoconus; Ophthalmology; 111(3) 440-6 (Mar. 2004).
49. Rabinowitz YS, Dong L, Wistow G: Gene expression profile studies of the human keratoconus corneas for NEIbank. A novel cornea expressed gene and the absence of transcripts for Aquaporin 5; Invest Ophthalmol Vis Sci; 46(4) 1239-46 (Apr. 2005).
50. Tang YG1, Rabinowitz YS, Taylor KD, Li X, et al: A genome-wide linkage scan in a multi-generation Caucasian pedigree identifies a novel susceptibility locus for keratoconus on chromosome 5q14.3-q21.1; Genet Med; 7(6):397-405 (July-Aug. 2005).
51. Binder PS, Lindstrom RL, Stulting RD, Donnenfeld E, Wu H, McDonnell P, Rabinowitz YS: Keratoconus and corneal ectasia after LASIK; J Refract Surg; 21(6):749-52 (Nov.-Dec. 2005).
52. Binder PS, Lindstrom RL, Stulting RD, Donnenfeld E, Wu H, McDonnell P, Rabinowitz YS: Keratoconus and corneal ectasia after LASIK; J Cat Refract Surg; 31(11):2035-8 (Nov. 2005).
53. Li X, Rabinowitz YS, Tang YG, Picornell Y, Taylor KD, Hu M, Yang H: Two-stage genome-wide linkage scan in keratoconus sib pair families; Invest Ophthalmol Vis Sci; 47(9):3791-5, (2006).
54. Rabinowitz YS: INTACS for keratoconus; Int Ophthalmol Clin; 46(3):91-103 (2006).
55. Rabinowitz YS, Ignacio T, Li X, Maguen E: Intacs using the femtosecond laser (Intralase) for keratoconus–6 months results on 20 eyes; J Refract Surg; 22(8):764-71 (Oct. 2006).
56. Aldave AJ, Yellore VS, Salem AK, Yoo GL, Rayner, SA, Yang H, Tang, GT, Piconell Y, Rabinowitz YS: No VSX1 gene mutations associated with keratoconus; Invest Ophthalmol Vis Sci ; 47(7):2820-2 (2006).
57. Rabinowitz YS: Ectasia after laser in situ keratomileusis; Current Opinions in Ophthalmology; 17 (5):421-6, (2006).
58. Sarayba MA, Maguen E, Salz J, Rabinowitz YS, Ignacio TS: Femtosecond laser keratome creation of partial thickness donor corneal buttons for lamellar keratoplasty; J Refract Surg; 23(1):58-65 (Jan. 2007).
59. Rabinowitz YS: Intacs for Keratoconus; Current Opinions in Ophthalmology; 18(4):279-83 (July 2007).
60. Jafri B, Li X, Rabinowitz YS: Wavefront analysis in the early detection of keratoconus; Refractive and Corneal Surgery (in press 2007).
61. Li X, Yang H, Rabinowitz YS: Longitudinal study of familial influences on Keratoconus; Experimental Eye Research (in press 2007).
62. Tang G, Rabinowitz YS: VSX1 mutations in keratoconus; CORNEA (in press 2007).
63. Li X, Rabinowitz YS: Classification scheme for keratoconus based on videokeratography and clinical signs; J. of Cataract and Refractive Surgery (in press 2007).
64. Rabinowitz YS, Tang G: Aquaporin 5: A molecular maker for keratoconus with potential for detecting subclinical disease; American Journal of Ophthalmology (in press 2007).
Books:
Rabinowitz YS, Wilson SE, Klyce SD, Editors
A Color Atlas of Corneal Topography: Interpreting Videokeratography Igaku-Shoin Medical Publishers; New York– Tokyo; 1993.
Book Chapters:
1. Corneal Topography and its Optics. In Duane’s. Clinical Ophthalmology; Duane T, Jaeger ED, Eds., Volume 1; Chapter 65; pgs.1-15 (1996).
2. Congenital Anomalies of the Lens in Emery and Rimoin's Principles and Practice of Medical Genetics. Third Edition (1996).Churchill Livingston Press. Rimoin D, Connor, J, Michael, Pyeritz RE, Eds., Vol. II; pgs. 2535-2554.
3. Keratoconus. In Genetic Diseases of the Eye. Traboulsi E, Ed.; Oxford University Press; Chapter 13: 267-284.
4. Pellucid Marginal Degeneration. In: Current Ocular Therapy 5. Fraunfelder F, Ed. (2002); Section 20; Cornea; pgs. 371-373.
5. Corneal Topography: Corneal Curvature and Optics, Clinical Applications, and Wavefront Analysis. In Bennett ES, Weissman BA. Clinical Contact Lens Practice. Lippincott, Williams and Wilkins; pgs. 215-232.
6. Ectatic Disorders of the Cornea. In Smolin and Thoft’s The Cornea. Scientific Foundations and Clinical Practice. Fourth Edition. Foster CS, Azar DT, Dohlman CH, Eds.; Lippincott Williams and Wilkins; pgs. 889-911.
7. Definition, Etiology, and Diagnosis of Keratoconus. In Treating Irregular Astigmatism and Keratoconus. Alio JL, Belda JI, Eds. Highlights of Ophthalmology; pgs. 241-260.
8. Corneal Topography and Wavefront Analysis. Optics and Clinical applications. In Clinical Ophthalmology. Duane T, Jaeger E, Eds. (2006) (in press 2007).
9. Pellucid Marginal Degeneration. In Current Ocular Therapy 9; Fraunfelder F, (Editor) 6, Section 20.
10. Keratoconus. Diagnosis and early detection. Ertan, et al.
11. Intracorneal Ring Segments. Femtosecond Lasers in Ophthalmology; American Academy of Ophthalmology
