Curriculum Vitae -
Anthony John Bron, M.D.
August 2007
BUSINESS ADDRESS:
T10 Warnborough Road
Oxford. OX2 6HZ
Telephone:
(01865) 248996
Fax Number:
(01865) 794508
QUALIFICATIONS:
B.Sc. (Physiol.) 2:1, 1957
M.R.C.S., L.R.C.P., October 1960
M.B., B.S., March 1961
D.O., October 1963
F.R.C.S., May 1968
FRCOphth, F Med Sci. 1998
PRESENT APPOINTMENT:
Emeritus Professor of Ophthalmology, University of Oxford; Research Associate, Nuffield Laboratory of Ophthalmology University of Oxford; Research Associate, Department of Biochemistry, University of Oxford.
ACADEMIC HONORS AND AWARDS:
Beaney Prize in Pathology, (shared), 1960
Laidlaw Prize in Clinical Physiology, 1960
Alexander-Piggott-Wernher Memorial Trust Fellowship, (1964–1965) (Medical Research Council)
Sir William Lister Traveling Fellowship Royal College of Surgeons, (1964–1965)
President Royal Society of Medicine Ophthalmic Section, (1986–88); President Elect, (1984–85)
Elected to the Society of Scholars, Johns Hopkins University, May 1992
Chairman: Association for Eye Research 1992–1995 (AER).
Vice President: Joint European Research Meetings in Ophthalmology and Vision 1994–1995 (JERMOV).
Founder Member, Academy Medical Science 1998
European Secretary: ISER 1999–2003
President, EVER 2002–2003
EDUCATION:
City of London School, London 1947–1954
Guy's Hospital, London,1954–1961
2nd M.B.,1954–1957
B.Sc (2:1) ,1957–1958
Clinical Training, 1958–1961
PUBLISHED SCIENTIFIC ARTICLES:
(Dr. Bron has published approximately 240 articles; only the most recent are listed here.)
Nutrition supplements and the eye. Brown, N., Bron A.J., Harding J.J., and Dewar H.M. Eye, 12, 127-133. (1998).
Topical delivery of microvolumes using a forced-flow system (Optidyne). Bron, A.J., Tiffany, J.M. and Embleton. In: Lacrimal Gland, Tear Film and Dry Eye Syndromes. (Sullivan, D.A. Ed) Vol. 2, pp, Plenum New York. (1998).
Meibomian gland and tear film lipids: structure, function and control. Bron, A.J. and Tiffany, J.M. In: Lacrimal Gland, Tear Film and Dry Eye Syndromes. (Sullivan, D.A. Ed) Vol. 2, pp Plenum New York. (1998).
Comparison of the efficacy and safety of two eye gels in the treatment of dry eyes: Lacrinorm and Viscotears. Bron, A.J., Daubas, P., Siou-Mermet, R. and Trinquand, C. Eye, 12, 839-847. (1998).
The Lens and cataract in diabetes. Bron, A.J., Brown, N.A., Harding, J.J. and Ganea E., Int Ophthalmol. Clin. 38, 37-67. (1998)
Reflective meniscometry: a non-invasive method to measure tear meniscus curvature. Yokoi, N., Bron, A.J., Tiffany, J.M., Brown, N.A., Hsuan, J.D. and Fowler, C. Br. J. Ophthalmol. 83, 92- 97. (1999).
Physical properties of stimulated and unstimulated tears. Pandit, J.C., Nagyova,B., Bron, A.J. and Tiffany, J.M. Exp. Eye Res. 68, 247-253. (1999).
Sugars including erythronic and threonic acids in human aqueous humour. Harding, J. J., Hasssett, P., Rixon, K.C., Bron, A.J., and Harvey, D.J. Curr. Eye Res. 19, 131-136, (1999).
Deposits and proteoglycan changes in primary and recurrent granular dystrophy of the cornea. Ahktar, S., Meek, K.M., Ridgway A.E.A., Bonshek, R.E., Bron A. J. Arch. Ophth. 117 310-321, (1999).
The Ageing lens. Bron, A.J., Vrensen, G.F.J.M., Koretz, J., Maraini, G. and Harding, J.J. Ophthalmologica. 214, 86-104, (2000).
5–Hydroxy tryptamine 1A – Agonists: potential use in glaucoma. Evidence from animal studies. Osborne, N.N., Wood, J.P.M., Melena, J., Chao, H-M., Nash, M.S., Bron A. J., Chidlow G. Eye (14) 3B. 454-463 (2000)
The Genetics of the Corneal Dystrophies: What have we learned in the last 25 years? Bron, A.J. Cornea (19) 5pp 699-711 (2000).
Reflective Meniscometry, A New Field of Dry Eye Assessment. Yokoi, N., Bron, A.J., Tiffany, J.M. and Kinoshita, S.Cornea 19 (Suppl. 1) S37-S43. 2000).
The effect of hydration and matrix composition on solute diffusion in rabbit sclera. Boubriak, O.A., Urban, J.P.G.,Meek, K.M., Akhtar, S and Bron, A.J. Exp. Eye Research Exp Eye Res. Nov;71(5):503-14 2000.
Congenital Hereditary Endothelial Dystrophy and Band Keratopathy in an infant with corpus callosum agenesis. Akhtar, S., Bron, A.J., Meek, K.M. and Bennett, K. submitted to Cornea, (20), 5 pp. 547-552 (2001).
Aqueous antibiotic levels after intravitreal therapy for endophthalmitis. Haider, A., Hassett, P., Suhawardy, J., Bowler, I.C.J.W. and Bron, A.J. Retina (21) 3pp 210-213 (2001).
The molecular genetics of Bowman's layer dystrophies Aldave A.J., McLeod S.D., Bron A.J. Cornea, (20), 6 pp. 672-674 (2001).
The architecture of the corneal stroma. Bron A.J. Brit. J. Ophthalmol, (85), 4 pp. 379-381(2001).
Survey of Ophthalmology: Introduction Bron A.J. Survey of Ophthalmology, (45), SUPPL. 2 (2001).
Diagnosis of dry eye. Bron A.J. Survey of Ophthalmology, (45), SUPPL. 2 Cited 12 times (2001).
Ultrastructural morphology and expression of proteoglycans, Big-h3, tenascin-C, fibrillin-1, and fibronectin in bullous keratopathy Akhtar S., Bron A.J., Hawksworth N.R., Bonshek R.E., Meek K.M.Brit. J. Ophthalmol, (85), 6 pp. 720-731. Cited 4 times (2001).
Posterior subcapsular and nuclear cataract after vitrectomy. Hsuan JD, Brown NA, Bron AJ, Patel CK, Rosen PH. J Cataract Refract Surg. 2001 Mar;27(3):437-44.
Using osmolarity to diagnose dry eye: A compartmental hypothesis and review of our assumptions. Bron A.J., Tiffany J.M., Yokoi N., Gouveia S.M. Advances in Experimental Medicine and Biology, (506 B), pp. 1087-1095 (2002).
Assessment of meibomian gland function by a newly-developed laser Meibometer. Komuro A., Yokoi N., Kinoshita S., Tiffany J.M., Bron A.J., Suzuki T. Advances in Experimental Medicine and Biology, (506 A), pp. 517-520 (2002).
The Roche European American Cataract Trial (react): A randomized clinical trial to investigate the efficacy of an oral antioxidant micronutrient mixture to slow progression of age-related cataract. Chylack Jr. L.T., Brown N.P., Bron A., Hurst M., Kopcke W., Thien U., Schalch W. Ophthalmic Epidemiology, (9), 1 pp. 49-80 (2002).
The Cambridge Symposium: September 2002. Bron A.J. Eye, (17), 8 pp. 851 (2003).
Grading of corneal and conjunctival staining in the context of other dry eye tests Bron A.J., Evans V.E., Smith J.A. Cornea, (22), 7 pp. 640-650 (2003).
Retention of reversibly thermo-gelling timolol on the human ocular surface studied by video meniscometry. Ishibashi T., Yokoi N., Bron A.J., Tiffany J.M., Komuro A., Kinoshita S. Current Eye Research, (27), 2 pp. 117-122. Cited 1 times (2003).
Cytarabine-induced corneal toxicity. Lochhead J., Salmon J.F., Bron A.J. Eye, (17), 5 pp. 677-678 (2003).
The molecular chaperone alpha crystallin incorporated into red cell ghosts protects membrane Na/K-ATPase against glycation and oxidative stress Derham B.K., Ellory J.C., Bron A.J., Harding, J.J. European Journal of Biochemistry, (270), 12 pp. 2605-2611 (2003).
Differential effects of aging on transport properties of anterior and posterior human sclera Boubriak O.A., Urban J.P.G., Bron A.J. Experimental Eye Research, (76), 6 pp. 701-713 (2003).
Dynamic changes in tear meniscus curvature at the rigid contact lens edge. Yokoi N., Maruyama K., Kinoshita S., Bron A.J., Tiffany J.M. Cornea, (22), 3 pp. 226-229 (2003).
A clinical description of Meibomian gland dysfunction. Foulks G. and Bron A.J. The Ocular Surface. 1: 107-126 (2003).
Experimental Eye Research: Editorial Bron A.J., Paterson C., Cunha-Vaz J. Experimental Eye Research, (78) (2004).
Functional aspects of the tear film lipid layer. Bron A.J., Tiffany J.M., Gouveia S.M., Yokoi N., Voon L.W. Experimental Eye Research, (78), 3 pp. 347-360 (2004).
The contribution of Meibomian disease to dry eye. Bron A.J. and Tiffany J.M. The Ocular Surface. 2: 149-164 (2004).
Clinical and ultrastructural findings in Mare’s tail lines of the corneal epithelium. Akhtar, S., Bron, A.J, Meek, K.M., Voon, L.W. Brit. J. Ophthalmol. 88: 964-867 (2004).
Yokoi N, Bron AJ, Tiffany JM, Maruyama K, Komuro A, Kinoshita, S. Relationship between tear volume and tear meniscus curvature. Arch Ophthalmol 2004; 122: 1265-9.
Gelatinous drop-like dystrophy in a child with developmental delay. Clinicopathological features and exclusion of the M1S1 gene. Akhtar, S., Bron A.J., Creer R.C. Guggenheim J.A., Meek, K.M. Eye. Feb; 19 (2):198-204 (2005).
Changes in collagen orientation in keratoconus corneas. Meek K.S., Tuft S., Huang Y., Singh S., Dennis S., Newton R., Bron A.J.. Invest Ophthal Vis Sci. 2005.
Understanding and treating dry eye symptoms in Sjögren’s syndrome. Bron, A J. Joan Patel memorial lecture Leeds, November 2004. BSSA Journal ## (2005).
Treatment of dry eyes. Bron, A J. pp in BSSA – Handbook, 2005.
Tuft S and Bron, A.J. Imaging the microstructural abnormalities of Meesmann corneal dystrophy by in vivo confocal microscopy. Letter relating to the article: Patel DV, Grupcheva CN, McGhee CN. Imaging the microstructural abnormalities of Meesmann corneal dystrophy by in vivo confocal microscopy. Cornea. 2005 Aug; 24(6):669-73. Cornea 2006; 25: 868; author reply-70.
Bron, A.J. Book Review. Nov 2005, New England J Med 353; 2519-2520, Smolin and Thoft’s, The Cornea: Scientific Foundations and Clinical Practice, Eds. C. Stephen Foster, T. Azar, C.H.Dohlman, Lippincott, Williams Wilkins, 2005.
Turner AW, Layton CJ, Bron AJ. Survey of eye practitioners' attitudes towards diagnostic tests and therapies for dry eye disease. Clin Experiment Ophthalmol 2005; 33: 351-5.
Tan MH, Chen SD, Rubinstein A, Bron AJ. Corneal perforation due to severe peripheral ulcerative keratitis in Crohn’s disease. Cornea 2006; 25: 628-30.
Osborne NN, Lascaratos G, Bron AJ, Chidlow G, Wood JP. A hypothesis to suggest that light is a risk factor in glaucoma and the mitochondrial optic neuropathies. Br J Ophthalmol 2006; 90: 237-41.
The occurrence of fibrillary lines during overnight orthokeratology: Case report: Cheung S. W., Cho, P., Bron, A.J., Chui, V., Chan, B. Ophthalmic and Physiological Optics. 2006; 26: 525-31.
Akhtar S, Voon LW, Bron AJ. The ultrastructure of superficial hypertrophic dendriform epitheliopathy after keratoplasty. Cornea 2006; 25: 623-7.
Bron A J, Aldave A, Akhtar S, Stewart H, Nischal K K. Inherited dystrophies and developmental anomalies of the cornea. Chapter 63, in Duanes’ Ophthalmology, Lipincott, Williams and Wilkins, Philadelphia, Eds. W. Tasman and E.A. Jaeger.
Book and Chapters
The Eye in the Inborn Errors of Metabolism. March of Dimes. Eds. Bergsma, D., Cotlier, E. and Bron, A.J. (1965)
Ocular Trauma. Bron, A.J. and Kaufman, D.V. Folia T Geigy 1977.
The Unquiet Eye: An educational slide-tape and booklet for Glaxo Ltd. 1981.
The Unquiet Eye. Bron, A.J. Glaxo, 1-97. 1983; Revised Edition, with C, Davey 1-100, 1987.
Lens Disorders: A Manual of Lens and Cataract, N.A.P Brown and A.J. Bron, Butterworths, 1996.
Ocular Trauma, with D. Kaufmann Geigy. Ref. 46 Folia Traumatologica Geigy 1977.
Lecture Notes in Ophthalmology, B James; C Chew; A J Bron; Blackwells Scientific. (1997); 2007
Wolff's Anatomy of the Eye and Orbit. 8th Edition. (1997). Chapman & Hall Completely revised with Prof. R. Warwick, and Professors Tripathi, R.C. and B. Chapters rewritten personally: orbital innervation, ocular appendages, ocular muscles and eye movement, cornea and sclera, the eyeball, anterior chamber, iris, ciliary body, vitreous, lens and zonule, visual pathway and autonomic system.
Ocular Infection: Investigation and Treatment in Practice, Seal, D. and Hayes J. and Bron. A.J. Martin Dunitz, (1998).
